According to a study published in JAMA Psychiatry, maternally reported Gastrointestinal (GI) symptoms are more common and more often persistent during the first 3 years of life in children with autism spectrum disorder (ASD) than in children with typical development (TD) or developmental delay (DD).
During a 10-year period (January 1, 1999, through December 31, 2008), women throughout Norway were recruited at the first prenatal ultrasonographic visit (approximately 18 weeks’ gestation). The study enrolled 95,278 mothers, 75,248 fathers, and 114,516 children. Three groups of children were defined: children with ASD (n = 195), children with DD and delayed language and/or motor development (n = 4636), and children with TD (n = 40 295).
The GI symptoms were based on maternal report of constipation, diarrhea, and food allergy/intolerance.